ComfortMax 30 AM + 30 PM vegetarian tabs - Life Extension

ComfortMAX™ delivers two potent ingredients: palmitoylethanolamide (PEA) and honokiol, a compound derived from Magnolia bark. By promoting nerve comfort in two separate yet complementary ways, the ingredients in ComfortMAX™ help to inhibit nerve discomfort.
The reasons for physical discomfort vary, but the way we experience that discomfort doesn't. That's why we’ve created ComfortMAX™.

ComfortMAX™ Benefits
Dual-action formula helps alleviate minor nerve discomfort
Helps you stay comfortable throughout the day
Provides morning and nighttime doses for around-the-clock support
According to the National Institutes of Health, nearly 25 million Americans experience daily discomfort. This kind of discomfort can affect mood, mobility and quality of life. The reasons for physical discomfort vary, but the way we experience that discomfort doesn’t: Our peripheral nerves are responsible for delivering sensory information (an itch, temperature change, physical pressure, etc.) to the brain. And that’s where ComfortMAX™ comes in.
Palmitoylethanolamide (PEA)
Palmitoylethanolamide (PEA) is a unique kind of fatty acid that can inhibit discomfort. Your body naturally produces PEA as part of a healthy inflammatory and immune response. In fact, PEA inhibits the secretion of compounds from mast cells, a type of white blood cell. Over time, our mast cells decrease in number, causing our remaining mast cells to work harder.
That can make them overly sensitive, activating processes linked to nerve discomfort. By inhibiting compounds released by mast cells, PEA promotes your body’s natural response to uncomfortable nerve stimuli at the cellular level.
PEA’s efficacy has been demonstrated in multiple clinical trials. In a randomized controlled trial following 636 patients over a period of three weeks, 600 mg of PEA every day significantly improved scores that measured relative comfort and quality of life. In a smaller randomized controlled trial, patients reported that PEA outperformed standard care for discomfort when taken for two weeks.
Honokiol
Honokiol is a naturally occurring lignan compound derived from several species of magnolia, many of which have been used in traditional Asian medicine for centuries. Now, scientists are discovering that honokiol has applications for nerve health and comfort.
Honokiol has been shown to support the “calming” GABA receptors in the brain, which in turn helps alleviate discomfort. Furthermore, honokiol is quickly taken up into the brain in animal models, making it an ideal ingredient for nerve health and comfort.
Innovative Daytime & Nighttime Formula
ComfortMAX™ has been formulated to be taken twice a day, one tablet in the morning and one tablet at night, right before bed, for day and night support. Each package of ComfortMAX™ provides a 30-day supply.

AM
Supplement Facts
Serving Size: 1 AM Vegetarian Tablet (White)
Amount Per Serving % Daily Value
Calcium (as calcium carbonate) 60 mg 5%
Palmitoylethanolamide (PEA) 600 mg **
**Daily Value not established.
PM
Supplement Facts
Serving Size: 1 PM Vegetarian Tablet (Blue)
Amount Per Serving % Daily Value
Calcium (as calcium carbonate) 30 mg 2%
Palmitoylethanolamide (PEA) 600 mg **
Honokiol [from magnolia extract (bark)] 180 mg **
**Daily value not established.

Suggested use
Read entire box and follow directions carefully.
Take one (1) AM tablet in the morning and one (1) PM tablet before bed, or as recommended by a healthcare practitioner.

Other ingredients
AM
Microcrystalline cellulose, croscarmellose sodium, hydroxypropyl methylcellulose, silica, stearic acid, vegetable stearate, maltodextrin, glycerin.
PM
Microcrystalline cellulose, croscarmellose sodium, hydroxypropyl methylcellulose, silica, stearic acid, vegetable stearate, maltodextrin, glycerin, spirulina extract color.

Warnings
The blue PM tablet may cause mild sedation in some people. Take at bedtime.
Store in a cool dry place.
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is damaged.
Consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.